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The dosage of chloroquine phosphate is often expressed or calculated as the base.

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ChloroquineCQis a lysosomotropic antimalarial drug that neutralizes lysosomal acidificationthus blocking autophagosomal degradation.

ARALEN is indicated for the suppressive treatment and for acute attacks of malaria due to PvivaxP.malariaePovaleand susceptible strains of PfalciparumThe drug is also indicated for the treatment of extraintestinal amebiasis.

When prolonged therapy with any antimalarial compound is contemplatedinitialbase lineand periodic ophthalmologic examinationsincluding visual acuityexpert slit-lampfunduscopicand visual field testsshould be performed.

The blood concentrations of chloroquine and desethylchloroquinethe major metabolite of chloroquinewhich also has antimalarial propertieswere negatively associated with log antibody titersChloroquine taken in the dose recommended for malaria prophylaxis can reduce the antibody response to primary immunization with intradermal human diploid-cell rabies vaccine.

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to avoid this, antacids and kaolin should not be taken in the two to three hours before or after taking your chloroquine dose.